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Up-regulation of peripheral benzodiazepine receptor system in hepatocellular carcinoma

✍ Scribed by I. Venturini; M.L. Zeneroli; L. Corsi; R. Avallone; F. Farina; H. Alho; C. Baraldi; C. Ferrarese; N. Pecora; M. Frigo; G. Ardizzone; A. Arrigo; R. Pellicci; M. Baraldi


Book ID
117175877
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
875 KB
Volume
63
Category
Article
ISSN
0024-3205

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Loss of heterozygosity (LOH) at 1p36 occurs in a number of solid tumors including hepatocellular carcinoma (HCC). Recently, a novel gene, p73, has been identified at 1p36.33. p73 is structurally and functionally related to p53 located at 17p13.1, which is a target for inactivation in HCCs. p73 produ