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Up-regulation of p21-activated kinase 1 by in vitro treatment with interleukin 1-beta and its increased expression in ovarian endometriotic cysts

✍ Scribed by Mi Young Lee; Sung Hoon Kim; Hyo Jin Ihm; Hee Dong Chae; Chung-Hoon Kim; Byung Moon Kang


Book ID
116478866
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
340 KB
Volume
96
Category
Article
ISSN
1556-5653

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## Abstract ## Objective Mitogen‐activated protein kinases (MAPKs) are activated by proinflammatory stimuli. MAPK phosphatases (MKPs), in particular MKP‐1, have been identified as endogenous negative regulators of MAPK activation. Since MAPKs are known to be important in rheumatoid arthritis (RA)