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Up-regulation of Na+–Ca2+ exchange activity by interferon-γ in cultured rat microglia

✍ Scribed by Takayuki Nagano; Yasushi Kawasaki; Akemichi Baba; Motohiko Takemura; Toshio Matsuda


Book ID
111178318
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
309 KB
Volume
90
Category
Article
ISSN
0022-3042

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Cultured rat glial cells display a Na+-Ca2+ exchange system located at the plasma membrane levels. This was evidenced by the Na+ (+dependency of a Na+ (0)-inhibitable influx of Ca2+, or reversal exchange mode. This antiporter has an external site where monovalent cations (K+, Li+, and Na+ were inves