Up-regulation of matrix in bovine articular cartilage explants by electric fields
โ Scribed by Carl T. Brighton; Wei Wang; Charles C. Clark
- Book ID
- 116292363
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 476 KB
- Volume
- 342
- Category
- Article
- ISSN
- 0006-291X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Isolated articular cartilage chondrocytes from 1-to 3-week-old male Holstein calf knee joints were formed into pellets containing 4 x lo6 isolated cells and were grown in tissue culture medium (minimum essential medium/NCTC 135) containing either 1 or 10% newborn calf serum (NBCS) in plastic Petri d
Objective. To determine whether matrix metalloproteinases (MMPs) degrade cartilage oligomeric matrix protein (COMP) to produce fragments similar to those found in synovial fluid (SF) from patients with arthritis. Methods. COMP fragments were generated in vitro by treating (a) bovine articular carti