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Up-regulation of divalent metal transporter 1 is involved in 1-methyl-4-phenylpyridinium (MPP+)-induced apoptosis in MES23.5 cells

โœ Scribed by Shuzhen Zhang; Jun Wang; Ning Song; Junxia Xie; Hong Jiang


Book ID
116781256
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
959 KB
Volume
30
Category
Article
ISSN
0197-4580

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## Abstract The reasons underlying the high iron content found in the substantia nigra (SN) of Parkinson's disease (PD) are largely unknown. We suppose, based on our previous studies, that the newly discovered iron transporter divalent metal transporter 1 (DMT1) might be involved in this SN iron ac