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Up-regulation of cytochrome P450 and phase II enzymes by xenobiotics in precision-cut tissue slices

โœ Scribed by Ioannides, Costas


Book ID
120654862
Publisher
Informa plc
Year
2012
Tongue
English
Weight
713 KB
Volume
43
Category
Article
ISSN
0049-8254

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Modulation of hepatic cytochromes P450 a
โœ Victoria Yoxall; Peter Kentish; Nick Coldham; Nikolai Kuhnert; Maurice J. Sauer; ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 279 KB

## Abstract The principal objectives of our study were to ascertain whether sulforaphane, at dietary levels of intake, modulates rat hepatic cytochrome P450 and phase II enzyme systems and to evaluate the impact of such changes in the chemopreventive activity of this isothiocyanate. Animals were ex