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Up-regulation of cyclooxygenase-2 expression by TSG-6 protein in macrophage cell line

✍ Scribed by Catalin Mindrescu; Junming Le; Hans-Georg Wisniewski; Jan Vilcek

Book ID
116290246
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
465 KB
Volume
330
Category
Article
ISSN
0006-291X

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## Abstract Augmented expression of protein kinase CK2 is associated with hyperproliferation and resistance to apoptosis in cancer cells. Effects of CK2 are at least partially linked to signaling via the Wnt/β‐catenin pathway, which is dramatically enhanced in colon cancer. Cyclooxygenase‐2 (COX‐2)