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Up-regulation of components of the renin-angiotensin system in the bile duct–ligated rat liver

✍ Scribed by Georgina Paizis; Mark E. Cooper; Josefa M. Schembri; Christos Tikellis; Louise M. Burrell; Peter W. Angus

Book ID
119756793
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
585 KB
Volume
123
Category
Article
ISSN
0016-5085

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Recent evidence indicates that the renin-angiotensin system (RAS) plays a major role in liver fibrosis. Here, we investigate whether the circulatory RAS, which is frequently activated in patients with chronic liver disease, contributes to fibrosis progression. To test this hypothesis, we increased c