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Up-Regulation of Bcl-xLExpression Protects CD40-Activated Human B Cells from Fas-Mediated Apoptosis

✍ Scribed by Xinhong Zhang; Li Li; Jongseon Choe; Stanislaw Krajewski; John C. Reed; Craig Thompson; Yong Sung Choi

Book ID: 112239657
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 180 KB
Volume: 173
Category: Article
ISSN: 0008-8749
DOI: 10.1006/cimm.1996.0260

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## Abstract In the present study we used a human follicular lymphoma cell line, HF1A3, as an __in vitro__ model for the antigen‐driven selection process in germinal centers. Apoptosis can be induced in HF1A3 cells by B cell receptor (BCR) stimulation, but the molecular mechanisms and kinetics of th