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Unwinding of DNA by actinomycin D binding

✍ Scribed by James C. Wang

Book ID
115744427
Publisher
Elsevier Science
Year
1971
Weight
344 KB
Volume
232
Category
Article
ISSN
0005-2787

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## Abstract Actinomycin D is an anticancer antibiotic best know for inhibiting transcription by binding double‐stranded DNA. Tight, sequence selective binding of actinomycin to single‐stranded DNA is also known, however, and is implicated in biological activities including inhibition of (βˆ’) strand