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Unwinding in old age: Mutations in the consensus helicase domains of the Werner syndrome gene

✍ Scribed by Mark S. Palmer


Book ID
114382050
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
208 KB
Volume
3
Category
Article
ISSN
1357-4310

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Werner syndrome and mutations of the WRN
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Werner syndrome (WS) is a pleiotropic disease of premature aging involving short stature, tight, atrophied, and/or ulcerated skin; a characteristic 'birdlike' facies and high, squeaky or hoarse voice; premature greying and thinning of the hair; and early onset cataracts. Additional common symptoms i