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Unusual Reactivity of Zinc Borohydride - Reduction of Amides to Amines

โœ Scribed by Narasimhan, S.; Madhavan, S.; Balakumar, R.; Swarnalakshmi, S.


Book ID
119966412
Publisher
Taylor and Francis Group
Year
1997
Tongue
English
Weight
156 KB
Volume
27
Category
Article
ISSN
0039-7911

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2-Alkyl-3-oxo amides were reduced to the corresponding syn-2-alkyl-3-hydroxy amides with high stereoselectivity by zinc borohydride. In the search for new stereoselective reducing agents, T. Nakata and T. .ll Oishi found that the reduction of 4-unsaturated (phenyl or carbon-carbon double bond) 2-alk