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Unusual phlorins from the oxidative coupling of pentapyrromethanes: their facile conversion to meso-substituted porphyrins

✍ Scribed by Jae-Won Ka; Chang-Hee Lee


Book ID
104230848
Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
74 KB
Volume
42
Category
Article
ISSN
0040-4039

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✦ Synopsis


Direct, oxidant-mediated intramolecular coupling of pentapyrromethanes afforded 5-aryl-5-(2%-pyrryl)-10,15,20-triarylporphyrin (phlorins) as single products. The outcome of the reaction is comparable with the oxidative coupling of tetrapyrromethanes. Treatment of obtained phlorins with trifluoroacetic acid resulted in exclusive elimination of the peripheral pyrrole affording meso-tetraarylporphyrins quantitatively. The rate of pyrrole elimination depends on the acid concentration. The selective binding with fluoride anion was also observed with a large association constant.