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Unusual glomerulopathy in a transgenic mouse strain

✍ Scribed by JW FINNIE; DE NOONAN; PS SMITH

Book ID
111407819
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
817 KB
Volume
75
Category
Article
ISSN
0005-0423

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## Abstract Summary: A Cre recombinase expression cassette was inserted into the X‐linked __Hprt__ locus by gene targeting in a mouse embryonic stem (ES) cell line isogenic to strain 129S1/SvImJ (129S1), then the transgene was introduced into 129S1 mice through ES cell chimeras. When females hemizy