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Unusual extramedullary relapses under imatinib mesylate treatment in chronic myeloid leukemia

✍ Scribed by Yavuz Beyazit; Salih Aksu; Murat Kekilli; Ibrahim C. Haznedaroglu; Sadettin Kilickap; Hakan Goker


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
107 KB
Volume
79
Category
Article
ISSN
0361-8609

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## Abstract Imatinib mesylate (IM) is the standard first‐line treatment for patients with chronic myeloid leukemia (CML). Surprisingly, 2–15% of patients achieving a complete cytogenetic response develop cytogenetic abnormalities in Philadelphia (Ph)‐negative cells. Following hematopoietic stem cel