Unusual behaviour of a hydrophobic benzimidazolemethanethiol in micellar esterolysis

✍ Scribed by N. Krati; A. Brembilla; P. Lochon

• Book ID: 104232772
• Publisher: Elsevier Science
• Year: 1989
• Tongue: French
• Weight: 208 KB
• Volume: 30
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)80328-2

✦ Synopsis

Description

of the unusual behaviour of the first term of a new series of straight-chain heterocyclic thiols (benzimidazolemethanethiols) in a micellar system, in the hydrolysis reaction of p-nitrophenylesters.

Cysteine proteases form a large class of enzymes, and their active site is known to contain both a cysteine thiol group and an imidazole heterocycle borne by a histidine residue.

In the field of enzyme model reactions, we have reported