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Unusual association of MLL rearrangement and secondary myelomonocytic leukemia in a 15-year-old patient treated for osteosarcoma

✍ Scribed by Bénédicte Brichard; Hélène A. Poirel; Christophe Chantrain; Sophie Dupont; Jeanne Marie Libouton; Jean Marie Scheiff; Christiane Vermylen

Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 250 KB
Volume: 31
Category: Article
ISSN: 0145-2126
DOI: 10.1016/j.leukres.2006.12.014

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Background. Secondary leukemia and myelodysplastic syndromes have been reported in patients following treatment for a wide range of neoplastic disorders. However, second malignancies after chemotherapy and/or irradiation for osteosarcoma are unusual. Procedure. We report the case of a 15-yearold gi