Untersuchungen zur Biosynthese des Harmins

✍ Scribed by K. Stolle; Doz. Dr. D. Gröger

• Publisher: John Wiley and Sons
• Year: 1968
• Tongue: English
• Weight: 574 KB
• Volume: 301
• Category: Article
• ISSN: 0365-6233
• DOI: 10.1002/ardp.19683010802

✦ Synopsis

Untersuchungen zur Biosynthese dee Harmins*) E&lle/saele Ane dem Inatitut fiir Bioohemie der WenZen der Denteohea Akade.de der Whnsahaften, (Eingegmgen em 27. November 1987) The bioqmthesia of harmine in Peganum harmela hae been etndied wing labelled oomponnda. With the emmptkm of the w boxyl p u p the carbon fbt0mS and the nitrogen atom of the alanine d e ~ chain are incorporated into hanniue from tqptophan. Trypbnhe-(&UC-uN) is p r a c t i d y an equally good pmurear aa tryptophan-(&"C-uN). In & to olarifs the 0 -O f the Ca-Unit Of the ~-carbolinee (El and c-10 of harmhe) aoetate-1.142, acetate-2-"C, pyr~vate-$-"C and pyrUV8b-3-'% to young plant43 of P. were adrrmvetered harmah. A specific incorporation wae obmmed after feeding ppvate-2-"0 into c-1 waa obeerved & feeding of eoetste-l'c.