𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Unsymmetrical 2,5-dialkylpyrrolidines via reductive amination of 1,4-diketones

✍ Scribed by Tappey H. Jones; James B. Franko; Murray S. Blum; H.M. Fales

Book ID
104213096
Publisher
Elsevier Science
Year
1980
Tongue
French
Weight
230 KB
Volume
21
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Efficient synthesis of unsymmetrical 1,4
Efficient synthesis of unsymmetrical 1,4-disubstituted-2,3-diketopiperazines via tandem reductive amination–cyclization
✍ Douglas C Beshore; Christopher J Dinsmore πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 French βš– 123 KB

Herein we report the efficient syntheses of 1,4-disubstituted-2,3-diketopiperazines and 1,4,5-trisubstituted-2,3-diketopiperazines, which feature a tandem reductive amination and acylation. Aliphatic and aromatic primary amines serve as viable nucleophiles under the mild reaction conditions.