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Unstabilized Azomethine Ylides for the Stereoselective Synthesis of Substituted Piperidines, Tropanes, and Azabicyclo[3.1.0] Systems

✍ Scribed by Ischay, Michael A.; Takase, Michael K.; Bergman, Robert G.; Ellman, Jonathan A.


Book ID
120055014
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
908 KB
Volume
135
Category
Article
ISSN
0002-7863

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ChemInform Abstract: Application of meso
✍ Katharina Bica; Peter Gaertner πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 32 KB πŸ‘ 1 views

## Abstract Acrylic ester derivatives (I) possessing meso‐hydrobenzoin derived chiral auxiliaries undergo cycloaddition with the azomethine (II) to give the highly substituted pyrrolidines (III) with up to 87% e.e.