Unsaturated ketenes: A study of their formation and rearrangement by tandem mass spectrometry and low-temperature infrared spectroscopy

Flash-vacuum pyrolysis of 1-acylbenzotri

Flash-vacuum pyrolysis of 1-acylbenzotriazole: Direct observation of cyclopenta-2,4-dienylidenemethaneimines by tandem mass spectrometry and low-temperature infrared spectrometry

✍ André Maquestiau; Didier Beugnies; Robert Flammang; Beat Freiermuth; Curt Wentru 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 585 KB

## Abstract A real‐time analysis of the flash‐vacuum pyrolysis products of 1‐acetylbenzotriazole (1) and 1‐benzoylbenzotriazole (2) was performed by tandem mass Spectrometry. In the temperature range 500‐600 °C, these compounds lose nitrogen, yielding __N__‐acetyl‐ and __N__‐benzoylcyclopenta‐ 2,4‐

Formation of oligomeric alkenylperoxides

Formation of oligomeric alkenylperoxides during the oxidation of unsaturated fatty acids: an electrospray ionization tandem mass spectrometry study

✍ Juan José Villaverde; Sónia A. O. Santos; Elisabete Maciel; Mário M. Q. Simões; 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 451 KB

This study reports the identification of oligomeric alkenylperoxides by electrospray ionization mass spectrometry (ESI‐MS) and tandem mass spectrometry (ESI‐MS^2^), during the oxidation of oleic, linoleic and linolenic acids with Fenton's (Fe^2+^/H~2~O~2~) and Fe^2+^/O~2~ systems. The reactions were

Study of Frozen Solutions of Nucleic Aci

Study of Frozen Solutions of Nucleic Acid Nitrogen Bases by Means of Low Temperature Fast-atom Bombardment Mass Spectrometry

✍ Oleg A. Boryak; Marina V. Kosevich; Vadim S. Shelkovsky; Yuriy P. Blagoy 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 339 KB 👁 2 views

A simple liquid–liquid extraction with h

A simple liquid–liquid extraction with hexane for low-picogram determination of drugs and their metabolites in plasma by high-performance liquid chromatography with positive ion electrospray tandem mass spectrometry

✍ Yuan-Qing Xia; Daisy B. Whigan; Mohammed Jemal 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 246 KB 👁 3 views

Four sensitive, specific and accurate methods, based on high-performance liquid chromatography (HPLC) with positive ion electrospray tandem mass spectrometry (MS/MS) coupled with liquid-liquid extraction (LLE), have been developed and validated for the low-picogram determination of two drug candidat

Isolation of circulating metabolites in

Isolation of circulating metabolites in drug discovery using high-performance liquid chromatography, and their identification by liquid chromatography coupled with tandem mass spectrometry and nuclear magnetic resonance spectroscopy

✍ Hong Kim; Wenqing Feng; Tze-Ming Chan; Diane Rindgen; Matthew Bryant; Kathleen A 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 221 KB 👁 3 views

Isolation of circulating metabolites in drug discovery using high-performance liquid chromatography, and their identification by liquid chromatography coupled with tandem mass spectrometry and nuclear magnetic resonance spectroscopy One of the major components of modern drug discovery is the structu