Unrestricted killer cells recognize an antigen controlled by a gene linked toTla
β Scribed by Kirsten Fischer Lindahl
- Book ID
- 105240883
- Publisher
- Springer-Verlag
- Year
- 1979
- Tongue
- English
- Weight
- 308 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0093-7711
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Five monoclonal antibodies were established by the fusion of mouse myeloma cells (NS.1) with spleen cells from A and (A x C3H/An)F1 mice hyperimmunized with 70Z/3 tumor cells. These antibodies recognized a new antigenic specificity provisionally called Ly-m20.2. In direct cytotoxicity assays, 60 per
## Abstract We have identified an antigen recognized by cytolytic T lymphocytes (CTL) on the autologous tumor cells of a nonsmall cell lung cancer patient. The antigenic peptide, presented by HLAβB\*5201 molecules, was encoded by a mutated sequence in the gene coding for the C subunit of transcript