Duchenne muscular dystrophy (DMD) is a progressive and lethal neuromuscular disorder caused by a defective gene on the X chromosome. There is no effective treatment and the biochemical defect is yet unknown. Mapping of the DMD locus to band Xp21 in the short arm of the X chromosome has given rise to
Unraveling the mysteries of Duchenne and Becker muscular dystrophy
โ Scribed by Craig L. Hyser
- Publisher
- Springer-Verlag
- Year
- 1989
- Tongue
- English
- Weight
- 371 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1044-7393
No coin nor oath required. For personal study only.
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The indirect approach to carrier detection and prenatal diagnosis of Duchenne and Becker muscular dystrophies based on the study of DNA polymorphisms closely linked to this gene has been followed by five Italian laboratories in the study of 106 pedigrees. Out of 354 women studied up to 1 May 1987, 1