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Unraveling the genetics of complex diseases: Susceptibility genes for rheumatoid arthritis and psoriasis

✍ Scribed by Yonghong Li; Ann B. Begovich


Book ID
116885581
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
312 KB
Volume
21
Category
Article
ISSN
1044-5323

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## Abstract ## Objective Rheumatoid arthritis (RA) has an estimated genetic contribution of 30–50%, approximately one‐third of which arises from the major histocompatibility complex on 6p21.3. Many studies have implicated alleles of DRB1 that encode a shared epitope. However, several recent studie