The easily prepared chiral tertiary amino alcohol 1a was found to catalyze the reaction of alkynylzinc reagents with various aldehydes to generate chiral propargylic alcohols with moderate-to-good enantioselectivities. The mechanism of the reaction is also discussed in this Letter. A novel theoretic
โฆ LIBER โฆ
Unmodified chiral primary amino alcohol as a new ligand for enantioselective alkynylation of aldehydes
โ Scribed by Zhou Xu; Jincheng Mao; Yawen Zhang
- Book ID
- 119216533
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 185 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1566-7367
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