Unmeasured nitrogen losses in pediatric patients treated with peritoneal dialysis

✍ Scribed by Osamu Uemura; Takuhito Nagai; Satoshi Yamakawa; Katsumi Ushijima; Takuji Yamada; Yoshiko Hibi; Haruka Mimatsu; Yasuhito Yamasaki

• Publisher: Wiley (John Wiley & Sons)
• Year: 2010
• Tongue: English
• Weight: 120 KB
• Volume: 39
• Category: Article
• ISSN: 0090-2934
• DOI: 10.1002/dat.20496

✦ Synopsis

rea kinetics should be considered during solute removal by peritoneal dialysis (PD), especially in children. As growth involves protein anabolism, it is generally recommended that children have higher protein and calorie intake than adults. The National Kidney Foundation's Kidney Disease Outcomes Quality Initiative (NKF-K/DOQI) 2008 nutritional pediatric guidelines have recommended protein intake levels of 1.8 g/kg/day in infants younger than 6 months of age, 1.5 g/kg/day in infants aged 7-12 months, 1.3 g/kg/day in children aged 1-3 years, 1.1 g/kg/day in children aged 4-13 years, and 1.0 g/kg/day in children aged 14-8 years. 1 Thus, dialysis dosage may have to be greater in pediatric patients than in adults to achieve an equivalent blood urea nitrogen (BUN) level. We therefore assessed unmeasured nitrogen losses in children undergoing PD to deter-mine whether children require an increased dialysis dosage compared with adults.