Unique T Cell Antagonist Properties of the Exact Self-Correlate of a Peptide Antigen Revealed by Self-Substitution of Non-Self-Positions in the Peptide Sequence
✍ Scribed by Tony Schountz; Joel P. Kasselman; Stephanie R. Ford; Joseph S. Murray
- Book ID
- 112239470
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 164 KB
- Volume
- 168
- Category
- Article
- ISSN
- 0008-8749
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## Abstract We analyzed the sera of patients with melanoma to define the human humoral autoantibody profile towards HMW‐MAA. Computational proteome scanning using the non‐self‐discrimination principle as a guide led to the individuation of the low‐similarity HMW‐MAA~781–789~RATVWMLRL peptide fragme