Development of anaplastic lymphoma kinas
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Rongshi Li; Stephan W. Morris
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Article
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2008
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John Wiley and Sons
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English
⚖ 433 KB
## Abstract Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase (RTK) involved in the genesis of several human cancers; indeed, ALK was initially identified in constitutively activated and oncogenic fusion forms—the most common being nucleophosmin (NPM)‐ALK—in a non‐Hodgkin's lymphoma (N