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Unique regulation of SOST, the sclerosteosis gene, by BMPs and steroid hormones in human osteoblasts

✍ Scribed by May Kung Sutherland; James C Geoghegan; Changpu Yu; David G Winkler; John A Latham

Book ID: 116318958
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 547 KB
Volume: 35
Category: Article
ISSN: 8756-3282
DOI: 10.1016/j.bone.2004.04.019

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## Abstract We investigated the effects of oscillatory flow in regulating the gene expressions of type I collagen (COL1, the main component of human bone tissues) and osteopontin (OPN, the key gene for calcium deposition) in human osteoblast‐like (MG‐63) cells, and the roles of mitogen‐activated pr