Bullous systemic lupus erythematosus is a rare blistering condition with a distinctive combination of clinical, histological and immunopathologic features that together constitute a unique bullous disease phenotype. It is often associated with autoimmunity to type VII collagen. Here we report a chil
Unique Presentation of Systemic Lupus Erythematosus
β Scribed by E. Burkhalter
- Publisher
- John Wiley and Sons
- Year
- 1973
- Tongue
- English
- Weight
- 75 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0004-3591
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## SUMMARY A 19βyearβold woman with a 6 month history of systemic lupus erythematosus (SLE) developed a widespread urticated, erythematous eruption associated with tense, fluidβfilled blisters, erosions and crusting. Biopsy showed subepidermal blistering with a prominent neutrophilic infiltrate. Di
Tissue i n j u r y o c c u r r i n g i n p a t i e n t s w i t h SLE appears t o be mediated p r i m a r i l y by complement f i x i n g immune complexes comprised o f autoantibodies and autoantigens. Cytotoxic antibodies which d i r e c t l y i n t e r a c t w i t h i n s i t u membrane antigens, e