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Design of lipid-based formulations for o

Design of lipid-based formulations for oral administration of poorly water-soluble drugs: Precipitation of drug after dispersion of formulations in aqueous solution

✍ Kazi Mohsin; Michelle A. Long; Colin W. Pouton 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 307 KB

This study was designed to investigate the precipitation of a lipophilic drug following dispersion of lipid formulations in water. The model drug fenofibrate was formulated in representative lipid delivery systems designed for oral administration, using medium chain glycerides, polysorbates, and pro