✦ LIBER ✦

Unilateral serous retinal detachment in a patient with thrombotic thrombocytopenic purpura

✍ Scribed by Jonathan A. Harris; Mark T. Friedman; Mala Varma

Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 37 KB
Volume: 23
Category: Article
ISSN: 0733-2459
DOI: 10.1002/jca.20165

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✦ Synopsis

Abstract

Ocular complications are a relatively common occurrence in patients with thrombotic thrombocytopenic purpura (TTP). Serous retinal detachment is a rare but reported complication, with most cases being bilateral and associated with concomitant hypertension. Therapeutic plasma exchange has been used to successfully treat patients with TTP. We report a case of a 46 year old woman who presented with TTP, received therapeutic plasma exchange, and developed unilateral serous retinal detachment with retinal pigment epithelial tear in the absence of reported hypertension. The increased perfusion pressure due to hypertension, combined with the choroidal vasculature damage from TTP are thought to lead to retinal epithelial tear. This suggests that although hypertension may play a role in retinal detachment in these patients, other mechanisms may be responsible. J. Clin. Apheresis, 2008. © 2008 Wiley‐Liss, Inc.

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