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Unilateral periodic limb movements during sleep in corticobasal degeneration

✍ Scribed by Jorge Iriarte; Manuel Alegre; Javier Arbizu; Purificación de Castro

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
1018 KB
Volume
16
Category
Article
ISSN
0885-3185

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✦ Synopsis

Abstract

Periodic limb movements in sleep (PLM) have been associated with several degenerative disorders and other focal or diffuse diseases. We present a patient with clinical diagnosis of corticobasal degeneration and sleep complaints, in whom video recording and polygraphic study confirmed the presence of right PLM. The unilaterality of the movements and the positron emission tomography findings (hypometabolism in the left frontoparietal, basal ganglia, and thalamic areas) suggest that the loss of inhibitory descending central pathways, with origin in the cortex or basal ganglia, may be involved in the pathogenesis of PLM. © 2001 Movement Disorder Society.

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