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Unilateral delayed opercularization in a case of Sotos' syndrome (cerebral gigantism)

✍ Scribed by P. G. Barth; L. Vlasveld; J. Valk


Publisher
Springer
Year
1980
Tongue
English
Weight
351 KB
Volume
20
Category
Article
ISSN
0028-3940

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We report on a child with apparent Sotos syndrome (cerebral gigantism) and partial duplication of the short arm of chromosome 20 mosaicism. Trisomy 20p11.2-p12.1 was diagnosed using cytogenetic and FISH studies. The somatostatin receptor 4 (SSTR4) gene is included in the duplicated segment. This sug

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A patient who developed a unilateral opercular syndrome following a cerebrovascular accident is described. Computed tomography showed that the lesion did not affect the opercular cortex, but involved deep white matter and the head of the caudate nucleus of the left hemisphere. Persistent hypophonia