Unified Nomenclature for Eph Family Receptors and Their Ligands, the Ephrins
β Scribed by Eph Nomenclature Committee
- Book ID
- 117267440
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 52 KB
- Volume
- 90
- Category
- Article
- ISSN
- 0092-8674
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π SIMILAR VOLUMES
## Background The tissue distributions and functions of Eph receptors and their ephrin ligands have been well studied, however less is known about their evolutionary history. We have undertaken a phylogenetic analysis of Eph receptors and ephrins from a number of invertebrate and vertebrate species
## Abstract Eph receptors and their ephrin ligands constitute the largest subfamily of receptor tyrosine kinases and are components of the cell signaling pathways involved during development. Eph and ephrin overexpression have been documented in a variety of human cancers including gastrointestinal