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Unfolding and Targeting Thermodynamics of DNA Stem-Loop Motifs

✍ Scribed by Khutshivilli, Irine; Prislan, Iztok; Lee, Hui-Ting; Lee, Cynthia; Marky, Luis A.

Book ID: 122104461
Publisher: Biophysical Society
Year: 2013
Tongue: English
Weight: 37 KB
Volume: 104
Category: Article
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2012.11.2352

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## Abstract ## Background Short hairpin RNA (shRNA) libraries are considered to comprise a powerful tool in genetic screening. Several library construction methods have been proposed; these methods require between four and nine tedious reaction steps to construct the library. In the present study,