๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Unfavorable outcome of adrenal medullary transplant for Parkinson's disease

โœ Scribed by L. S. Forno; J. W. Langston

Book ID
104710311
Publisher
Springer-Verlag
Year
1991
Tongue
English
Weight
993 KB
Volume
81
Category
Article
ISSN
0001-6322

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โœฆ Synopsis

A 45-year-old woman with moderately severe parkinsonism underwent adrenal medullary autograft to the brain. The operation was performed in Mexico City. There were multiple post-operative complications, including worsening of the parkinsonism with almost complete loss of ability to communicate. Death from bronchopneumonia occurred 13 months after surgery. At autopsy the surgical tract was found to extend through the corpus callosum and into the thalamus on the opposite side. Residual necrotic adrenal tissue was found as a small round well-defined mass in the ventricle loosely attached to the left fornix. This case emphasizes the obvious risks of this still experimental procedure and the difficulties in obtaining a surviving and functional adrenal medullary graft.

๐Ÿ“œ SIMILAR VOLUMES

Autologous adrenal medullary transplant
Autologous adrenal medullary transplant in Parkinson's disease: Critical review of our results in 13 patients
โœ Massimo Porena; Silvestro Parziani; Elisabetta Costantini; Giuseppe Vespasiani; ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 445 KB

Autotransplantation of the adrenal medullary to the caudate nucleus has been proposed for severe Parkinson's disease (PD). We describe our experience in 13 patients using a transperitoneal approach to the medullary and craniotomy for the implant: the neurosurgical equipe's decision to opt for cranio

Neuropathological study 16 years after a
Neuropathological study 16 years after autologous adrenal medullary transplantation in a Parkinson's disease patient
โœ Katie Kompoliti; Yaping Chu; Kathleen M. Shannon; Jeffrey H. Kordower ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 84 KB

## Abstract To date, there is no clinicopathological correlation of adrenal medullary transplant cases in patients with survival beyond a few years. Postmortem examination of a brain from a patient with Parkinson's disease (PD), 16 years after autologous adrenal medullary transplant, was performed