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Unexplained decrease in measured oxygen saturation by pulse oximetry following injection of Lymphazurin 1% (isosulfan blue) during a lymphatic mapping procedure

✍ Scribed by Coleman, Robert L.; Whitten, Charles W.; O'Boyle, John; Sidhu, Bobbie

Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 56 KB
Volume: 70
Category: Article
ISSN: 0022-4790
DOI: 10.1002/(sici)1096-9098(199902)70:2<126::aid-jso12>3.0.co;2-p

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✦ Synopsis

A rare case of alteration in measured pulse oximetry during a lymphatic mapping procedure for cervical carcinoma is reported. Over a 5-min period following injection of perilesional Lymphazurin 1% dye (3 ml total), a profound pulse oximetry desaturation was observed. Concomitant arterial blood gas determinations confirmed patient's well-being. Interaction of this agent's absorptive spectroscopy and wavelengths used to measure oxygen saturation by commercial pulse oximetry devices is suspected.