Unexpected thermal rearrangement of N-alkoxycarbonyl imidazole acryl azides to imidazo[1,5-c]pyrimidinone or imidazo[4,5-c]pyridinone

✍ Scribed by Yuguo Jiao; Edward Valente; Solomon T. Garner; Xiaotang Wang; Hongtao Yu

• Publisher: Elsevier Science
• Year: 2002
• Tongue: French
• Weight: 83 KB
• Volume: 43
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(02)01174-7

✦ Synopsis

Rearrangement of alkoxycarbonyl imidazole acryl azides in phenyl ether at 200°C yields imidazo[1,5-c]pyrimidinone or imidazo[4,5-c]pyridinone derivatives, depending on the size of the alkoxy substituent.