The Enantioselective Synthesis of (+)-Es
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Wolfgang Oppolzer; David Anthony Roberts
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Article
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1980
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John Wiley and Sons
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German
β 176 KB
π 1 views
## Abstract The optically pure steroid (+)β**15** has been synthesized from the easily accessible (+)βcarboxylic acid **11** by a sequence of 7 steps in 50% overall yield. The key steps are the regioselective deprotonation/alkylation **7+13 β 14** and the thermal SO~2~βextrusion/cycloaddition **14