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Unexpected augmentation of mycophenolic acid pharmacokinetics in renal transplant patients receiving tacrolimus and mycophenolate mofetil in combination therapy, and analogous in vitro findings

✍ Scribed by Keith Zucker; Anne Rosen; Alexandra Tsaroucha; Ludmilla de Faria; David Roth; Gaetano Ciancio; Violet Esquenazi; George Burke; Andreas Tzakis; Joshua Miller


Book ID
117676553
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
715 KB
Volume
5
Category
Article
ISSN
0966-3274

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Pharmacokinetics of mycophenolic acid in
✍ Ashok Jain; Raman Venkataramanan; Tai Kwong; Ravi Mohanka; Mark Orloff; Peter Ab πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 132 KB

The bioavailability of mycophenolic acid (MPA) after oral administration of mycophenolate mofetil (MMF) has been reported to be more than 90% in healthy volunteers, and in kidney and thoracic organ transplant patients. Such information is limited in liver transplant (LTx) patients. The present study