Undetectable HIV-1 RNA load with the Cobas TaqMan v1.0 in a patient diagnosed at the time of primary HIV-1 infection
✍ Scribed by Jade Ghosn; Julie Galimand; Laurence Meyer; Diane Descamps; Astrid Vabret; Christiane Deveau; Patrick Yéni; Cécile Goujard; Christine Rouzioux; Marie-Laure Chaix
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 58 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0146-6615
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✦ Synopsis
Abstract
Diagnosis of primary HIV‐1 infection is challenging due to the presence of a serological window; thus, HIV‐1‐RNA quantitation and/or measurement of p24 antigenemia are recommended in such cases. A patient was diagnosed at the time of primary HIV‐1 infection, he harbored a CFR02_AG subtype virus; quantitation of plasma HIV‐1‐RNA yielded an undetectable result according to one commercial assay, while HIV‐1‐RNA was detectable when measured with three other assays. J. Med. Virol. 82:1816–1818, 2010. © 2010 Wiley‐Liss, Inc.