## Communicated by Francesco Giannelli Exogenous (e.g., environmental) mutagens produce characteristic patterns of mutation. In contrast, endogenous mutation processes likely are associated with an invariant pattern of mutation. Analysis of factor IX gene mutations among large samples of hemophili
โฆ LIBER โฆ
Understanding what determines the frequency and pattern of human germline mutations
โ Scribed by Arnheim, Norman; Calabrese, Peter
- Book ID
- 109952937
- Publisher
- Nature Publishing Group
- Year
- 2009
- Tongue
- English
- Weight
- 881 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1471-0056
- DOI
- 10.1038/nrg2529
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## Communicated by Albert de la Chapelle Hereditary diffuse gastric cancer (HDGC) is a cancer predisposition syndrome caused by germline mutation of the gene encoding the tumour-suppressor E-cadherin (CDH1). We describe the search for CDH1 mutations in 36 new diffuse gastric cancer families. All 1