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Understanding Tubulin/Microtubule−Taxane Interactions: A Quantitative Structure–Activity Relationship Study

✍ Scribed by Hansch, Corwin; Verma, Rajeshwar P.

Book ID
126116766
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
173 KB
Volume
5
Category
Article
ISSN
1543-8384

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## Abstract Breast cancer is the second leading cause of cancer death among women in the United States. Two taxane analogues, taxol and taxotere, are the most important antimitotic drugs currently in clinical use for the treatment of breast cancers. However, recent reports have indicated that the u