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Understanding trans platinum complexes as potential antitumor drugs beyond targeting DNA

✍ Scribed by A.G. Quiroga


Book ID
119298886
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
892 KB
Volume
114
Category
Article
ISSN
0162-0134

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## Abstract Modification and optimization of the anticancer drug cisplatin is of interest with respect to selective cell targeting and DNA binding efficiency. Attractive approaches contain both, modification of the platinum coordination sphere and design of hybrid molecules of the cisplatin binding