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Understanding the multiple functions of Nramp1

✍ Scribed by Jenefer M Blackwell; Susan Searle; Tapasree Goswami; E.Nancy Miller

Book ID
108488866
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
554 KB
Volume
2
Category
Article
ISSN
1286-4579

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✍ Maria Gazouli; Vassilios Atsaves; Gerassimos Mantzaris; Michalis Economou; Georg πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 265 KB

Background: Crohn's disease (CD) is characterized by chronic activation of macrophages. Natural resistance-associated macrophage protein 1 (NRAMP1) gene exerts many pleiotropic effects on macrophage functions. Hence, NRAMP1 may be also involved in the resistance to intracellular pathogens, and this