Understanding the mechanistic roles of30Kc6gene in apoptosis and specific productivity in antibody-producing Chinese hamster ovary cells
β Scribed by Wang, Zesong; Ma, Xuhui; Fan, Li; Rhee, Won Jong; Park, Tai Hyun; Zhao, Liang; Tan, Wen-Song
- Book ID
- 113025469
- Publisher
- Springer
- Year
- 2012
- Tongue
- English
- Weight
- 653 KB
- Volume
- 94
- Category
- Article
- ISSN
- 1432-0614
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## Abstract Mammalian cells are used for the production of numerous biologics including monoclonal antibodies. Unfortunately, mammalian cells can lose viability at later stages in the cell culture process. In this study, the effects of expressing the antiβapoptosis genes, __E1Bβ19K__ and __Aven__,