Understanding the effects of the polymer support on reaction rates and kinetics: knowledge toward efficient synthetic design

✍ Scribed by Daniel Walsh; Daqian Wu; Young-Tae Chang

• Book ID: 104414770
• Publisher: Elsevier Science
• Year: 2003
• Tongue: English
• Weight: 236 KB
• Volume: 7
• Category: Article
• ISSN: 1367-5931
• DOI: 10.1016/s1367-5931(03)00054-1

✦ Synopsis

Solid-phase organic synthesis (SPOS) has an ever-expanding role in the field of organic synthesis. Partially out of difficulty, and partially from the rapid speed of progress, few basic studies on the role of the physical structure of the resin have been undertaken, and the dissemination of the existing knowledge has been slow. Major advances have been made in the understanding of the many factors that govern a SPOS reaction's performance as a function of the choice of solid support.