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Understanding protein unfolding from molecular simulations

โœ Scribed by Rudesh D. Toofanny; Valerie Daggett


Book ID
112232636
Publisher
Wiley (John Wiley & Sons)
Year
2012
Tongue
English
Weight
570 KB
Volume
2
Category
Article
ISSN
1759-0876

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Steered molecular dynamics simulations o
โœ Hui Lu; Klaus Schulten ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 322 KB ๐Ÿ‘ 3 views

Steered molecular dynamics (SMD), a computer simulation method for studying force-induced reactions in biopolymers, has been applied to investigate the response of protein domains to stretching apart of their terminal ends. The simulations mimic atomic force microscopy and optical tweezer experiment