Mutations and protein stability
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John A. Schellman; Margaret Lindorfer; Richard Hawkes; Markus Grutter
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Article
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1981
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Wiley (John Wiley & Sons)
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English
โ 611 KB
## Abstract The comparative study of proteins which differ in primary structure by point mutations permits one to use thermodynamic experiments to obtain information about the role of specific amino acids in determining protein structure and stability. We have now determined the thermodynamic chang